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Bupropion is not used in pregnant or breastfeeding women, adolescents under 18 years, or in patients for whom contraindications exist due to interactions with other medications

Arterial tortuosity syndrome: homozygosity for two novel and one recurrent SLC2A10 missense mutations in three families with severe cardiopulmonary complications in infancy and a literature review

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However, the rate of decline can vary among individuals